Vinay Tergaonkar obtained his Ph.D. (2001) through an international cancer society (UICC) fellowship for collaborative research at Tufts University, Boston, USA. He has been a fellow (2001-2004) and a special fellow (2004-present) of the Leukemia and Lymphoma Society of America and conducted his postdoctoral studies at the Salk Institute for Biological Studies, La Jolla, California. He joined the Institute of Molecular and Cell Biology (IMCB), Singapore, in late 2005 as Principal Investigator and became a Senior Principal Investigator in 2010 and Research Director in 2015. He is also a Professor at Yong Loo Lin School of Medicine at National University of Singapore. He serves on Editorial Boards of 1) Science Advances (AAAS), 2) Molecular and Cellular Biology (American Society for Molecular Biology), 3) Biochemical Journal (Portland Press), 4) Critical Reviews in Oncology/Hematology (Elsevier Press), 5) BMC Research Notes (Biomed Central), 6) Telomeres and Telomerase, 7) Journal of Molecular Biology and Molecular Imaging, 8) Bioscience Reports and 9) Genome Instability & Diseases. Work from his lab has received international recognition including the British council development award (2014), the Premiers’ fellowship from Government of South Australia (2015) and University of Macau Distinguished Professorship (2019).
Cancer Cell Signalling & Biology, Genomics, Non-Coding RNAs, Novel anti-cancer strategies, Oncology drug development, Small Molecules, Peptide/siRNA therapeutics, Patient Derived xenografts, Orphan disease models.
dedicating our time on the bench.
I love solving problems, being dynamic, and understanding how things work. I started my bioinformatics career nearly 10 years ago studying ancient DNA (aDNA) and analyzing the genetic structure of human extinct populations. Since then, I've worked on multidisciplinary research projects where I acquired skills ranging from molecular biology and handling of C. elegans to image analysis and software development of web applications. I’ve authored 12 publications, created multiple software and bioinformatic pipelines for NGS analysis, and in my free time I like to cook and dance salsa. I look forward to share my expertise, keep improving myself, and for a future where I lead a small team of problem solver minded people like me.
Bioinformatics, genetics, shiny and web apps
After completing my masters at NUS in 2012, I joined SBIC/A*STAR and worked on the Cherenkov Luminescence Imaging (CLI) and the development of bioimaging probes for diagnosing metabolic diseases. Later at 2014, I moved to IMCB/A*STAR and involved in various projects till date which includes in vivo pharmacological services to external clients and in house projects, siRNA therapeutics for Idiopathic Pulmonary Fibrosis (IPF), PDX models for identifying new drug candidates, development of NIK inhibitors for cancer and fibrosis models and the role of RNA bindinf proteins on apoptosis.
in vivo PK/PD, PDX models, in vitro toxicity assessment, in vitro assays, immunoprecipitation, western blot, PCR, ELISA, IVIS imaging, in vivo fluorescence stereomicroscopy
I got my PhD in University of Otago, New Zealand. My thesis was about the mechanisms of endocrine treatment resistance in breast cancer and my interests are in tumour biology and evolution. I am also a connoisseur of Dad jokes and puns.
Cancer genetics, biochemistry, cell biology
I got PhD degree from NUS. My background is about the structure and function of RBPs in microRNA biogenesis. I joined IMCB in 2019 and start working on apoptosis. I like running, shopping and drama. We can be friends if you also like it.
Molecular biology, cell culture, biochemistry assays
I was a research officer who proceeded to pursue a PhD program in this lab. I am keen in the field of immunology and I like to discuss topics related to it. I am also easily amazed by new biotechnologies that includes spatial transcriptomics and I enjoy learning them.
I have a diploma in Veterinary Biosciences but went on to NTU to do my degree in Biological Sciences. I have experience working in a Non-Human Primate lab and also in a neuroscience lab during my university internship to study Alzheimer's Disease. I enjoy being on the bench and animal work, occasionally helping with other miscellaneous tasks like designing and making figures. During my free time, I pursue other hobbies like photography, calligraphy, baking, resin and jewellery making.
Hi, I graduated from University College London, United Kingdom with Master of Research in Biosciences ( Cell Biology). I have a keen interest in cell biology, signalling pathways and cancer biology. During my free time, I enjoy watching movies, playing games, and exploring good food.
My adventure started as an Assistant Lab Officer (ALO) with the Sequencing team, GIS in 2007. I further explored into Cancer Therapeutics followed by Translational Research (CAP and ISO13485 certification lab) teams within GIS as a Senior Research Officer. Now, I am privileged to be part of VT lab in IMCB. Impressed with a team of extremely dedicated and motivated talents, I hope to make my contributions impactful.
I graduated with a Diploma in Biotechnology from Ngee Ann Polytechnic in 2001. While juggling a growing family and my position as an ALO then, I attained a BSc. (1st Class Honours) in Business and Management Studies from University of Bradford, UK in 2008. I have always been self-directed and tenacious in achieving both professional and personal goals. It is my wish to see every group that I am in be successful in nurturing individuals that have a progressive career and happy lives.
Lab management, Grants and Project Management, Contracts and Agreements, Ethics and safety documentation, Budget and Procurement oversight and Talent development
Hi, I am Indonesian. I got my PhD from Soonchunhyang Institute of Medi-Bio Science, Korea in 2021, then I had one-year postdoctoral training experience under the same institution. My work mainly focused on the field of cancer signaling and inhibition, especially colon cancer, lung cancer, liver cancer, and leukemia. I also experienced to work in the adult HSCs hematopoiesis and expansion, as well as the development of the CAR-T/NK cells using these cells. Currently I am excited to continue and pursue my research interest in IMCB (VT lab) as research fellow. Aside from science, I am a foodie, like to watch K-drama, and like to shop^^. Ask me anything about Korean things, I will be happy to share it with you ^^.
Cancer signaling, cancer therapy, HSC transplantation, HSC expansion, Immunotherapy, several animal models of liver disease and cancers.
I am (going to be) a final year student Majoring in Life Sciences and Minoring in Public health at NUS! I am interested in cancer biology and cancer immunology. I am always open to learning more from others in the scientific field. I enjoy whipping up food whenever I can as a destressing activity!
Despite being a graduate from SIT with a Bachelor's Degree in Pharmaceutical Engineering, I have always enjoyed being in lab and harbours strong interest in Biological Sciences and scientific research in Biomedical Applications. Hence, I return to VT lab as a Research Officer, where I had my undergrad internship, to further my lab skills, lab management skill(s), and scientific knowledge alongside an aspiring research fellow. For leisure, I delight in cafes- and museums-hopping, photography, trekking, reading/writing poetry and sleeping.
I started my research journey at the Institute of Molecular and Cell Biology after being awarded the A*STAR Science Award (Polytechnic) in 2014-2016. For my polytechnic final year project (FYP), I worked under the tutelage of Prof Jonathan Loh and focused on dissecting the mechanistic role of splicing factor SRSF11 in human somatic cell reprogramming. I later attained my BSc. in Biological Sciences (1st Class Honours) from Nanyang Technological University in 2021. As a Nanyang Scholar, I worked closely with Dr Adrian Teo’s lab where I extensively utilized patient-derived human pluripotent stem cells for disease modelling. I have a strong innate interest in unveiling the molecular mechanisms underlying disease pathology. I hope that my research efforts will be able to bring forward promising strategies to make precision medicine a reality.
In my free time I enjoy reading up on history and playing JRPGs. Currently I am also trying to learn coding in various languages in hopes of programming my own game in the future!
I did my undergraduate and masters degree in the University of Manchester and worked at The Institute of Cancer Research (ICR) in London prior to starting my PhD programme. My research interest and experience focused on studying the signalling pathway in breast cancer subtypes, in 2D cells and 3D organoid cultures. Outside the lab, I enjoy rockclimbing, cooking and good coffee! (:
I always wanted to have my own company to have freedom for creating new technologies and applications to shape the future with novel and impactful solutions. After getting my PhD from NUS, I co-founded a start-up company, Denome Technologies, with the support of Prof. Vinay and A*STAR where we develop machine learning algorithms and kits for disease diagnosis and drug treatment response prediction. By using my molecular biology background and bioinformatics skills, I help to design NGS experiments and process NGS data including single cell RNA Sequencing and spatial transcriptomics in VT lab. Hoping to find better diagnostic biomarkers that can touch the lives of future generations. Wish me luck!
Bioinformatics, coding, machine learning, molecular techniques
I obtained my Bachelor's degree (Hons) in Biomedical Sciences and my Master of Research in Cancer in Newcasatle University, United Kingdom. I enjoy exploring the oncogenic signalling pathways driving cancer, and am thrilled to be using state-of-the-art technologies that open up new experimental opportunities to fill the gaps in our understanding of the disease in pursuit of developing targeted therapeutic interventions.
I am a final year undergraduate majoring in Life Sciences (specialisation in biomedical science) at the National University of Singapore (NUS). My research interests are centred around exploring disease mechanisms and learning about their underlying molecular and cellular pathways. I aspire to contribute meaningfully to the collective knowledge that informs effective therapeutic strategies. In my free time, I enjoy reading, watching movies and playing the piano!
I got my PhD from Southeast University, China which focussed on the characterisation of the role of novel oncogene TRPS1 in tumorigenesis and cancer development in the breast cancer context. My research focus is on the role of long noncoding RNAs in inflammation and cancer.
Long noncoding RNA; NFκB; RNA helicase; inflammatory bowel disease;glioblastoma
Hi, I come from China. I got my undergraguate degree from Zhejiang Sci-Tech University, China. I just join VT lab in 2022 and to learn more knowledge about gene editing, cancer and apoptosis. In my free time, I love swimming, running and reading.
I studied undergraduate Biochemistry at the University of Manchester. I have a keen interest in the dynamics of signalling networks, and my PhD focuses on the dynamics of the NF-κB signalling pathway. I am interested in understanding the role of microRNAs in controlling these dynamics. I enjoy running and climbing.
I am a medical biotechnologist pursuing a PhD programme focused on breast cancer metastasis in bone. I did my first 2 years of PhD research in London funded by QMUL and I am currently in Singapore as an ARAP student joint with NTU. I have previously researched about CAR-T cell therapy for pancreatic cancer at Barts Cancer Institute in London. I am keen on the link between oncology and immunology.
I obtained my PhD (2022) from Indian Institute of Science, Bangalore, India. In my PhD, I explored the role of epigenetics in glioma development and progression. I joined Prof. Vinay lab at IMCB, ASTAR, as a research fellow. I am passionate about epigenetic regulations in the biological world, and always excited to explore emerging fields in biology. Beside science, I love reading, cooking, travelling, and trekking.
Cancer Genetics and Epigenetics, Molecular Biology, Cell signaling.
I am Nobendu Mukerjee, a passionate budding-researcher in Cell Biology, specializing in Molecular Virology and Cancer Biology and currently pursuing my Master's in Microbiology at West Bengal State University, India, I have an academic background from Ramakrishna Mission Vivekananda Centenary College and a research associate at Novel Global Community and Educational Foundation, Australia. My research is focused on understanding viral infections and cancer, with a specific interest in drug discovery through computational biology, targeting novel phyto-molecules for viral spike jamming. Presently, I am engaged in a project on Exosome mediated Proteolysis Targeting Chimeras (PROTACs) in viral infections, highlighting my skills in advanced therapeutic strategies and complex biomedical problem-solving.
Outside of my professional pursuits, I am passionate about drawing and enjoy cooking, often hosting culinary events for friends and colleagues. I am excited about joining the VT lab, looking forward to collaborating with peers in virology and cancer biology research.
Speaking of discovery, here’s a little scientific humor: Why did the cancer cell refuse to play hide and seek with the virus? Because whenever it tried to hide, the virus kept spiking the location! But as for me, I'm determined to turn this game around. In the world of virology and cancer research, you've got to 'mutate' to innovate!
Microbial assay, Molecular docking, Molecular Dynamic Simulations
I received my doctorate degree from Indian Institute of Technology, India that focussed on the viral genome targeting for antiviral drug discovery and vaccine development. Intrigued to understand the signalling pathways involved in different human diseases especially inflammatory diseases and cancer, I joined VT lab. I am excited to explore this opportunity to get hold of certain signalling components that can prove to be effective targets for treating cancer.
If you take me out of the lab, I like to try my hands on calligraphy and travel with my family. Moreover, being a foodie myself, I love to cook and host people. So, you are always welcome to my abode!!!
Biochemical and biophysical techniques, drug screening, cell culture, viral assays
I received my MSc. degree in Molecular Biology and Genetics from the Izmir Institute of Technology, Turkey. I started my research career in Singapore with a SIPGA fellowship followed by SINGA and completed my PhD at NUS Medical School in 2016. After my PhD training, I continued my research career as a Research Fellow at IMCB and successfully obtained OF-YIRG funding in 2018. Additionally, in 2019, I co-founded Denome Technologies, a business unit focusing on AI based gene expression technologies. Currently, I continue to pursue my research interest as a senior research fellow in IMCB, VT Lab.
Crispr Editing, lncRNAs, Inflammation, Epigenetic Analysis, Chromatin Interactions, Transcriptional Regulation.
I got my phD from Sun Yat-Sen University, China. I’m interested in studying the mechanism of cancer to explore novel biomarkers and therapeutic targets. During my phD, my thesis was about the role and mechanism of novel tumor suppressor gene OLFM1 in the development of colorectal cancer. In my spare time, I like reading science fiction and mystery novel.
I obtained a B.A. in Biology (Minor in Chemistry) from the University of Minnesota. During my undergraduate, I interned in Dr. David Weiner’s lab (University of Pennsylvania), where I studied the immunogenicity of DNA vaccine constructs for influenza A virus. I pursued Ph.D. as a SINGA awardee under the supervision of Dr. Vinay Tergaonkar (IMCB) and Dr. Andrew Tan (NTU), characterizing GREB1’s function in ERα-positive breast cancer. Currently, I am pursuing my passion for developing and engineering genome editing technologies capable of therapeutic application. My long-term goal is to create and translate powerful biotechnologies that empower scientific research and enhance human health.
I graduated from National University of Singapore with bachelor’s degree (Hons) in Life Sciences and minor in Public Health. For my Final Year Project, I worked on the biophysical mechanism for liquid–liquid phase separation of SARS-CoV-2 N protein and TAR DNA-binding protein 43 in Prof Song Jianxing’s Lab. I’m interested in molecular biology and genetic manipulations. In my free time, I enjoy learning designs and histories of vintage/antique jewelry.